The influence of diet and supplementation on premenstrual syndrome: narrative literature review
DOI:
https://doi.org/10.62827/nb.v24i2.3065Keywords:
Women's Health; Premenstrual Syndrome; Diet; Dietary Supplements.Abstract
Introduction: Premenstrual Syndrome (PMS) affects a large proportion of women during their childbearing years, manifesting itself through varied symptoms that precede menstruation and can compromise different aspects of daily life. Objective: The influence of diet and nutritional supplementation in reducing the symptoms associated with PMS, as well as their clinical implications, was described through recent scientific evidence. Methods: This is a narrative literature review, carried out based on publications indexed in the SciELO, PubMed, LILACS and ScienceDirect databases, with a time frame between 2019 and 2024, using DeCS (Health Sciences Descriptors) and MeSH (Medical Subject Headings) descriptors. The combination occurred through Boolean operators AND and OR. Results: The importance of a low glycemic index diet, rich in fruits, vegetables and whole grains for PMS is highlighted. Diets rich in sugar, caffeine, alcohol, and ultra-processed foods have been associated with worsening PMS symptoms. Supplementation with magnesium, vitamin B6, vitamin D, calcium, omega-3, zinc, and turmeric has been shown to be effective in modulating mood, reducing pain, and improving physical fitness. It was found that personalized nutritional interventions integrated with multidisciplinary clinical care offer safe and low-cost alternatives for managing PMS. Conclusion: Functional nutrition and nutritional supplementation should be considered relevant strategies for promoting women's health, contributing to physical and emotional well-being during this period of the menstrual cycle. Continuing research with robust methodologies, longer intervention times, and representative samples is essential to consolidate this evidence.
References
Muramatsu CH, Vieira OCS, Simões CC, Katayama DA, Nakagawa FH. Consequências da síndrome da tensão pré-menstrual na vida da mulher. Rev esc enferm USP [Internet]. 2001Sep;35(3):205–13. doi: https://doi.org/10.1590/S0080-62342001000300002
Silva CML da, Gigante DP, Carret MLV, Fassa AG. Estudo populacional de síndrome pré-menstrual. Rev Saúde Pública [Internet]. 2006Janeiro;40(1):47–56. doi: https://doi.org/10.1590/S0034-89102006000100009
Imai A, Ichigo S, Matsunami K, Takagi H. Premenstrual syndrome: management and pathophysiology. Clin Exp Obstet Gynecol. [Internet]. 2015;42(2):123-8. Available from: https://pubmed.ncbi.nlm.nih.gov/26054102/
Heidari H, Amani R, Feizi A, Askari G, Kohan S, Tavasoli P. Vitamin D Supplementation for Premenstrual Syndrome-Related inflammation and antioxidant markers in students with vitamin D deficient: a randomized clinical trial. Sci Rep. [Internet]. 2019 Oct 17;9(1):14939. doi: 10.1038/s41598-019-51498-x
Brown N, Martin D, Waldron M, Bruinvels G, Farrant L, Fairchild R. Nutritional practices to manage menstrual cycle related symptoms: a systematic review. Nutr Res Rev. [Internet]. 2024 Dec;37(2):352-375. doi: 10.1017/S0954422423000227
Nülüfer E, Duygu MD. The Relationship Between Premenstrual Syndrome and Dietary Habits and Nutrients Intake: Descriptive and Analytical CrossSectional Study. Clin Exp Health Sci. [Internet]. 2024; 14: 510-516 doi: 10.33808/clinexphealthsci.1421123
Robinson J, Ferreira A, Iacovou M, Kellow NJ. Effect of nutritional interventions on the psychological symptoms of premenstrual syndrome in women of reproductive age: a systematic review of randomized controlled trials. Nutr Rev. [Internet]. 2025 Feb 1;83(2):280-306. doi: 10.1093/nutrit/nuae043
Shobeiri F, Araste FE, Ebrahimi R, Jenabi E, Nazari M. Effect of calcium on premenstrual syndrome: A double-blind randomized clinical trial. Obstet Gynecol Sci. [Internet]. 2019 Jan;60(1):100-105. doi: 10.5468/ogs.2017.60.1.100
Oboza P, Ogarek N, Wójtowicz M, Rhaiem TB, Olszanecka-Glinianowicz M, Kocełak P. Relationships between Premenstrual Syndrome (PMS) and Diet Composition, Dietary Patterns and Eating Behaviors. Nutrients. [Internet]. 2024 Jun 17;16(12):1911. doi: 10.3390/nu16121911
Kevser İ, Bilge NYB, Ahsen DK. The Effect of Calcium on Premenstrual Syndrome: A Meta-Analysis Study. J CLIN MED KAZ. [Internet]. 2025;22(1):42-8. doi: https://doi.org/10.23950/jcmk/15827
Ella R. Motzko. Accessible Dietar Accessible Dietary Inter y Interventions for the Pr entions for the Prevention and ention and Management of Common Menstrual Disorders: A Systematic Review. Augsburg University. [Internet]. 2024; Site: https://idun.augsburg.edu/etd/1645
Sullivan BJ, Kadam SD. Brain-Derived Neurotrophic Factor in Neonatal Seizures. Pediatr Neurol. [Internet]. 2021 May;118:35-39. Doi: 10.1016/j.pediatrneurol.2021.01.011
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